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In large myelinated human motor neurons,impulses travel at about


A) the speed of light.
B) 186,000 miles per second.
C) 1 meter per second.
D) 60 meters per second.
E) 100 meters per second.

F) A) and B)
G) A) and C)

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A neuron normally fires when


A) its sodium-potassium pumps are stimulated.
B) there is an EPSP.
C) there is an IPSP.
D) the degree of depolarization on the axon adjacent to the hillock exceeds the threshold of excitation.
E) its buttons are stimulated.

F) B) and C)
G) A) and E)

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Drugs that facilitate the activity of the synapses of a particular neurotransmitter are said to be __________ of that neurotransmitter.


A) facilitators
B) agonists
C) antagonists
D) autoreceptors
E) endorphins

F) A) and D)
G) B) and D)

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Dopamine is not an effective treatment for Parkinson's disease because


A) dopaminergic neurons are restricted to the PNS.
B) Parkinson's disease is a cholinergic dysfunction.
C) Parkinson's disease is a noradrenergic dysfunction.
D) d'Orta is the treatment of choice.
E) dopamine does not readily penetrate the blood-brain barrier.

F) B) and E)
G) A) and E)

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The first event in the generation of an action potential is the opening of __________-activated sodium channels.

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Once released,neurotransmitter molecules typically produce signals in postsynaptic neurons by


A) binding to presynaptic receptors.
B) binding to postsynaptic receptors.
C) entering postsynaptic neurons.
D) binding directly to calcium ions.
E) attaching to vesicles.

F) A) and E)
G) A) and C)

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Discuss three ways that drugs produce agonistic effects and three ways that they produce antagonistic effects.Provide specific examples.

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35% for describing three mechanisms of a...

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Which neurotransmitters are often released from string-of-beads axons?


A) monoamines
B) amino acids
C) glutamate and GABA
D) soluble gases
E) peptides

F) B) and E)
G) B) and D)

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Drugs that degrade vesicles and cause the neurotransmitter molecules to leak into the cytoplasm,where they are destroyed by enzymes,are


A) receptor blockers.
B) agonists of the neurotransmitter.
C) antagonists of the neurotransmitter.
D) autoreceptor blockers.
E) amino acids.

F) A) and E)
G) B) and D)

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When a small-molecule neurotransmitter molecule binds to an ionotropic receptor,the


A) cell fires.
B) cell stops firing.
C) ligand is deactivated.
D) associated ion channel opens or closes.
E) EPSP gradually increases.

F) A) and D)
G) A) and C)

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Glycine,aspartate,and glutamate are


A) amino acid neurotransmitters.
B) small-molecule neurotransmitters.
C) transmitters at fast-acting, directed synapses.
D) building blocks of proteins.
E) all of the above

F) None of the above
G) All of the above

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EPSPs are


A) graded responses.
B) postsynaptic responses.
C) transmitted decrementally.
D) depolarizations.
E) all of the above

F) C) and E)
G) A) and C)

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A change in the resting potential of a postsynaptic dendrite from -70 mV to -72 mV is called


A) an IPSP.
B) an EPSP.
C) a depolarization.
D) both A and C
E) both B and C

F) B) and D)
G) B) and C)

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Many buttons contain two sizes of vesicles; the larger ones typically contain


A) small-molecule neurotransmitters.
B) neuropeptides.
C) acetylcholine.
D) dopamine.
E) glutamate.

F) None of the above
G) A) and B)

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Vesicles travel from the cell body to the buttons


A) on action potentials.
B) along microtubules.
C) at a rate of about 40 centimeters per second.
D) at a rate of about 40 centimeters per day.
E) both B and D

F) A) and E)
G) C) and D)

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Sodium-potassium pumps maintain the resting membrane potential by transporting


A) Na⁺ ions into neurons.
B) K⁺ ions into neurons.
C) Na⁺ ions out of neurons.
D) both A and B
E) both B and C

F) B) and D)
G) A) and B)

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Which of the following are considered to be small-molecule neurotransmitters?


A) neuropeptide transmitters
B) monoamine neurotransmitters
C) amino acid neurotransmitters
D) both A and B
E) both B and C

F) A) and B)
G) A) and C)

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Nitric oxide


A) is a soluble gas neurotransmitter.
B) is considered to be an unconventional neurotransmitter.
C) participates in retrograde synaptic transmission.
D) all of the above
E) both A and B

F) A) and D)
G) C) and D)

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This drug is a muscarinic acetylcholine antagonist; it is an extract of the belladonna plant; and it has pupil-dilating effects:


A) atropine.
B) curare.
C) morphine.
D) opium.
E) librium.

F) B) and D)
G) B) and E)

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The brief period of time immediately after the initiation of an action potential,when it is absolutely impossible to initiate another one in the same neuron,is called the


A) threshold of excitation.
B) threshold of inhibition.
C) absolute refractory period.
D) IPSP.
E) relative refractory period.

F) A) and E)
G) All of the above

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