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Cell-to-cell contact is required for transduction to occur.

A) True
B) False

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Synthesis of a repressible enzyme is stopped by the


A) substrate binding to the repressor.
B) corepressor-repressor complex binding to the operator.
C) corepressor binding to the operator.
D) allosteric transition.
E) end product binding to the promoter.

F) B) and C)
G) A) and D)

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The miRNAs in a cell


A) are responsible for inducing operons.
B) are a part of the eukaryotic ribosome.
C) allow different cells to produce different proteins.
D) are a part of the prokaryotic ribosome.
E) are found in prokaryotic cells.

F) C) and D)
G) A) and C)

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Figure 8.3 - Metabolic Pathway  Gene a Gene b Enzyme A  Enzyme B  Compound A  Compound B  Compound C \begin{array} { c c } &\text { Gene } a & \text { Gene } b \\&\downarrow & \downarrow \\&\text { Enzyme A } & \text { Enzyme B } \\&\downarrow & \downarrow \\\text { Compound A } & \rightarrow &\text { Compound B } \rightarrow \text { Compound C }\end{array} -In Figure 8.3, if enzyme A is an inducible enzyme,


A) compound B would bind to enzyme A directly.
B) compound C would react with gene a directly.
C) compound C would bind to the repressor for Gene a.
D) compound A would react with enzyme B directly.
E) compound A would bind to the repressor for Gene a.

F) A) and E)
G) A) and B)

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E

Figure 8.2 Figure 8.2    -In Figure 8.2, base 2 (and ONLY the base)  is covalently bound/attached to A)  deoxyribose. B)  phosphate. C)  thymine. D)  ribose. E)  The answer cannot be determined based on the information provided. -In Figure 8.2, base 2 (and ONLY the base) is covalently bound/attached to


A) deoxyribose.
B) phosphate.
C) thymine.
D) ribose.
E) The answer cannot be determined based on the information provided.

F) A) and C)
G) A) and B)

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Table 8.2 Codon on mRNA and corresponding amino acid  UUA  leucine  UAA  nonsense  GCA  alanine  AAU  asparagine  AAG  lysine UGC cysteine  GUU  valine UCG,UCU serine \begin{array} { | l | l | l | l | } \hline \text { UUA } & \text { leucine } & \text { UAA } & \text { nonsense } \\\hline \text { GCA } & \text { alanine } & \text { AAU } & \text { asparagine } \\\hline \text { AAG } & \text { lysine } & \mathrm { UGC } & \text { cysteine } \\\hline \text { GUU } & \text { valine } & \mathrm { UCG } , \mathrm { UCU }& \text { serine } \\\hline\end{array} -Refer to Table 8.2. What is the sequence of amino acids encoded by the following sequence of bases in a strand of DNA (pay attention to the polarity of the DNA here) ? 3? ATTACGCTTTGC


A) Translation would stop at the first codon.
B) asparagine-arginine-lysine-alanine
C) asparagine-cysteine-valine-serine
D) leucine-arginine-lysine-alanine
E) The answer cannot be determined based on the information provided.

F) B) and E)
G) A) and D)

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Which of the following is NOT a product of transcription?


A) rRNA
B) a new strand of DNA
C) tRNA
D) mRNA
E) None of the answers are correct; all of these are products of transcription.

F) B) and D)
G) A) and B)

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Recombination will always alter a cellʹs genotype.

A) True
B) False

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Transposition (insertion of a transposon into a DNA sequence) results in the formation of base substitution mutations in a cellʹs DNA.

A) True
B) False

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According to the operon model, for the synthesis of an inducible enzyme to occur, the


A) repressor must bind to the operator.
B) end-product must not be in excess.
C) substrate must bind to the enzyme.
D) repressor must not be synthesized.
E) substrate must bind to the repressor.

F) B) and E)
G) All of the above

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An enzyme that makes covalent bonds between the sugar of one nucleotide and the phosphate groups in another nucleotide in DNA is


A) RNA polymerase.
B) DNA ligase
C) DNA helicase.
D) transposase.
E) DNA polymerase.

F) D) and E)
G) A) and D)

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The miRNAs in a cell inhibit protein synthesis by forming complementary bonds with rRNA.

A) True
B) False

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Figure 8.2 Figure 8.2    -In Figure 8.2, if base 4 is thymine, what is base 4ʹ? A)  guanine B)  adenine C)  cytosine D)  thymine E)  uracil -In Figure 8.2, if base 4 is thymine, what is base 4ʹ?


A) guanine
B) adenine
C) cytosine
D) thymine
E) uracil

F) A) and D)
G) A) and C)

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Mutations that are harmful to cells occur more frequently than those that benefit cells.

A) True
B) False

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In the Ames test, any colonies that form on the control should be the result of spontaneous mutations.

A) True
B) False

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The initial effect of ionizing radiation on a cell is that it causes


A) DNA to break.
B) base substitutions.
C) the formation of highly reactive ions.
D) bonding between adjacent thymines.
E) the cells to get hot.

F) C) and D)
G) A) and E)

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An enzyme that catalyzes the cutting and resealing of DNA, and is translated from insertion sequences, is


A) RNA polymerase.
B) DNA ligase.
C) DNA helicase.
D) transposase.
E) DNA polymerase.

F) A) and E)
G) B) and E)

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Figure 8.4 Figure 8.4   In Figure 8.4, the antibiotic chloramphenicol binds the 50S large subunit of a ribosome as shown (the light gray area is the large subunit, while the black shape is the drug) . From this information you can conclude that chloramphenicol A)  prevents translation in eukaryotes. B)  prevents translation in prokaryotes. C)  prevents transcription in eukaryotes. D)  prevents mRNA-ribosome binding. E)  prevents transcription in prokaryotes. In Figure 8.4, the antibiotic chloramphenicol binds the 50S large subunit of a ribosome as shown (the light gray area is the large subunit, while the black shape is the drug) . From this information you can conclude that chloramphenicol


A) prevents translation in eukaryotes.
B) prevents translation in prokaryotes.
C) prevents transcription in eukaryotes.
D) prevents mRNA-ribosome binding.
E) prevents transcription in prokaryotes.

F) C) and D)
G) A) and E)

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B

Conjugation differs from reproduction because conjugation


A) transcribes DNA to RNA.
B) replicates DNA.
C) transfers DNA vertically, to new cells.
D) copies RNA to make DNA.
E) transfers DNA horizontally, to nearby cells without those cells undergoing replication.

F) A) and C)
G) None of the above

Correct Answer

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Figure 8.3 - Metabolic Pathway  Gene a Gene b Enzyme A  Enzyme B  Compound A  Compound B  Compound C \begin{array} { c c } &\text { Gene } a & \text { Gene } b \\&\downarrow & \downarrow \\&\text { Enzyme A } & \text { Enzyme B } \\&\downarrow & \downarrow \\\text { Compound A } & \rightarrow &\text { Compound B } \rightarrow \text { Compound C }\end{array} -In Figure 8.3, if compound C reacts with the allosteric site of enzyme A, this would exemplify


A) competitive inhibition.
B) transcription.
C) feedback inhibition.
D) a mutation.
E) repression.

F) All of the above
G) None of the above

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C

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