Question 1

Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol prevents microtubule depolymerization. Thus, Taxol stops mitosis by interfering with which of the following structures or processes?

Accepted Answer

A)   the mitotic spindle
B)   cytokinesis
C)   centriole duplication
D)   chromosome condensationE) B) and C)
F) A) and C)

Question 2

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Accepted Answer

A)   spindle formation
B)   spindle attachment to kinetochores
C)   movement of chromosomes to the poles during anaphase
D)   cleavage furrow formation and cytokinesisE) B) and C)
F) C) and D)

Question 3

Which of the following molecules is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?

Accepted Answer

A)   PDGF
B)   MPF
C)   cyclin
D)   CdkE) B) and D)
F) B) and C)

Question 4

Which of the following molecules is released by platelets in the vicinity of an injury?

Accepted Answer

A)   PDGF
B)   MPF
C)   cyclin
D)   CdkE) A) and D)
F) B) and C)

Question 5

At what stage of the cell cycle is the cyclin component of MPF destroyed?

Accepted Answer

A)   in late G₁
B)   at mid-S phase
C)   in early G₂
D)   in late ME) A) and B)
F) None of the above

Question 6

The decline of MPF activity at the end of mitosis is due to

Accepted Answer

A)   the destruction of the protein kinase Cdk.
B)   decreased synthesis of Cdk.
C)   the degradation of cyclin.
D)   the accumulation of cyclin.E) A) and D)
F) B) and C)

Question 7

Several organisms, primarily protists, have what are called intermediate mitotic organization. What is the most probable hypothesis about these intermediate forms of cell division?

Accepted Answer

A)   They represent a form of cell reproduction that must have evolved completely separately from those of other organisms.
B)   They rely on totally different proteins for the processes they undergo.
C)   They may be more closely related to plant forms that also have unusual mitosis.
D)   They show some but not all of the evolutionary steps toward complete mitosis.E) A) and D)
F) A) and C)

Question 8

In a diploid cell with 5 chromosome pairs (2n = 10) , how many centromeres will be found in a nucleus at G2 of the cell division cycle?

Accepted Answer

A)   5
B)   10
C)   20
D)   40E) C) and D)
F) B) and C)

Question 9

Movement of the chromosomes during anaphase would be most affected by a drug that prevents which of the following events in mitosis and cell division?

Accepted Answer

A)   nuclear envelope breakdown
B)   elongation of microtubules
C)   shortening of microtubules
D)   formation of a cleavage furrowE) C) and D)
F) A) and D)

Question 10

Which of the following molecules is a protein maintained at steady levels throughout the cell cycle that requires cyclin to become catalytically active?

Accepted Answer

A)   PDGF
B)   MPF
C)   cyclin
D)   CdkE) A) and B)
F) C) and D)

Question 11

For a chemotherapeutic drug to be useful for treating cancer cells, which of the following characteristics is most desirable?

Accepted Answer

A)   It is safe enough to prevent all apoptosis.
B)   It does not interfere with metabolically active cells.
C)   It specifically inhibits cells entering G₀.
D)   It specifically inhibits rapidly dividing cells.E) A) and B)
F) A) and C)

Question 12

FtsZ is a bacterial cytoskeletal protein that forms a contractile ring involved in binary fission. Its function is analogous to ________.

Accepted Answer

A)   the cleavage furrow of eukaryotic animal cells
B)   the cell plate of eukaryotic plant cells
C)   the mitotic spindle of eukaryotic cells
D)   the microtubule-organizing center of eukaryotic cellsE) B) and C)
F) A) and D)

Question 13

If there are 40 centromeres in a cell at anaphase of mitosis, how many chromosomes will be found in each daughter cell following cytokinesis?

Accepted Answer

A)   10
B)   20
C)   40
D)   80E) B) and D)
F) A) and D)

Question 14

Motor proteins require which of the following structures or molecules to function in the movement of chromosomes toward the poles of the mitotic spindle?

Accepted Answer

A)   intact centromeres
B)   a microtubule-organizing center
C)   ATP as an energy source
D)   intact cohesinE) A) and B)
F) A) and C)

Question 15

G₁ is associated with which of the following cellular events?

Accepted Answer

A)   normal growth and cell function
B)   DNA replication
C)   the beginning of mitosis
D)   break down of the nuclear membraneE) A) and B)
F) B) and D)

Question 16

Cell A has half as much DNA as cells B, C, and D in a mitotically active tissue. Cell A is most likely in

Accepted Answer

A)   G₁.
B)   G₂.
C)   prophase.
D)   metaphase.E) A) and C)
F) B) and C)

Question 17

Once a cell enters mitosis, the molecules that activate division must be turned off. What happens to MPF during mitosis?

Accepted Answer

A)   It is completely degraded.
B)   It is phosphorylated by a Cdk, which inactivates it.
C)   The cyclin component of MPF is degraded.
D)   The Cdk component of MPF is degraded.E) B) and C)
F) A) and B)

Question 18

Scientists isolate cells in various phases of the cell cycle. They isolate a group of cells that have 1 1/2 times more DNA than G₁ phase cells. What is the most likely part of the cell cycle from which these cells were isolated?

Accepted Answer

A)   between the G₁ and S phases in the cell cycle
B)   in the G₂ phase of the cell cycle
C)   in the M phase of the cell cycle
D)   in the S phase of the cell cycleE) B) and C)
F) B) and D)

Question 19

Use the figure to answer the question below.
The unlettered circle at the top of the figure shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A to E show various combinations of these chromosomes.

What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis?

Accepted Answer

A)   B
B)   C
C)   D
D)   EE) None of the above
F) A) and B)

Question 20

A cleavage furrow is ________.

Accepted Answer

A)   a ring of vesicles forming a cell plate
B)   the separation of divided prokaryotes
C)   a groove in the plasma membrane between daughter nuclei
D)   the space that is created between two chromatids during anaphaseE) A) and B)
F) All of the above

Exam 12: The Cell Cycle

Once a cell enters mitosis, the molecules that activate division must be turned off. What happens to MPF during mitosis?

Correct Answer
verified

If there are 40 centromeres in a cell at anaphase of mitosis, how many chromosomes will be found in each daughter cell following cytokinesis?

Correct Answer
verified

At what stage of the cell cycle is the cyclin component of MPF destroyed?

Correct Answer
verified

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Correct Answer
verified

Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol prevents microtubule depolymerization. Thus, Taxol stops mitosis by interfering with which of the following structures or processes?

Correct Answer
verified

Which of the following molecules is a protein maintained at steady levels throughout the cell cycle that requires cyclin to become catalytically active?

Correct Answer
verified

G₁ is associated with which of the following cellular events?

Correct Answer
verified

Which of the following molecules is released by platelets in the vicinity of an injury?

Correct Answer
verified

Scientists isolate cells in various phases of the cell cycle. They isolate a group of cells that have 1 1/2 times more DNA than G₁ phase cells. What is the most likely part of the cell cycle from which these cells were isolated?

Correct Answer
verified

In a diploid cell with 5 chromosome pairs (2n = 10) , how many centromeres will be found in a nucleus at G2 of the cell division cycle?

Correct Answer
verified

Motor proteins require which of the following structures or molecules to function in the movement of chromosomes toward the poles of the mitotic spindle?

Correct Answer
verified

Correct Answer
verified

Movement of the chromosomes during anaphase would be most affected by a drug that prevents which of the following events in mitosis and cell division?

Correct Answer
verified

Cell A has half as much DNA as cells B, C, and D in a mitotically active tissue. Cell A is most likely in

Correct Answer
verified

Several organisms, primarily protists, have what are called intermediate mitotic organization. What is the most probable hypothesis about these intermediate forms of cell division?

Correct Answer
verified

A cleavage furrow is ________.

Correct Answer
verified

For a chemotherapeutic drug to be useful for treating cancer cells, which of the following characteristics is most desirable?

Correct Answer
verified

FtsZ is a bacterial cytoskeletal protein that forms a contractile ring involved in binary fission. Its function is analogous to ________.

Correct Answer
verified

Which of the following molecules is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?

Correct Answer
verified

The decline of MPF activity at the end of mitosis is due to

Correct Answer
verified

Exam 12: The Cell Cycle

Once a cell enters mitosis, the molecules that activate division must be turned off. What happens to MPF during mitosis?

Correct AnswerverifiedShow Answer

If there are 40 centromeres in a cell at anaphase of mitosis, how many chromosomes will be found in each daughter cell following cytokinesis?

Correct AnswerverifiedShow Answer

At what stage of the cell cycle is the cyclin component of MPF destroyed?

Correct AnswerverifiedShow Answer

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Correct AnswerverifiedShow Answer

Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol prevents microtubule depolymerization. Thus, Taxol stops mitosis by interfering with which of the following structures or processes?

Correct AnswerverifiedShow Answer

Which of the following molecules is a protein maintained at steady levels throughout the cell cycle that requires cyclin to become catalytically active?

Correct AnswerverifiedShow Answer

G₁ is associated with which of the following cellular events?

Correct AnswerverifiedShow Answer

Which of the following molecules is released by platelets in the vicinity of an injury?

Correct AnswerverifiedShow Answer

Scientists isolate cells in various phases of the cell cycle. They isolate a group of cells that have 1 1/2 times more DNA than G₁ phase cells. What is the most likely part of the cell cycle from which these cells were isolated?

Correct AnswerverifiedShow Answer

In a diploid cell with 5 chromosome pairs (2n = 10) , how many centromeres will be found in a nucleus at G2 of the cell division cycle?

Correct AnswerverifiedShow Answer

Motor proteins require which of the following structures or molecules to function in the movement of chromosomes toward the poles of the mitotic spindle?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Movement of the chromosomes during anaphase would be most affected by a drug that prevents which of the following events in mitosis and cell division?

Correct AnswerverifiedShow Answer

Cell A has half as much DNA as cells B, C, and D in a mitotically active tissue. Cell A is most likely in

Correct AnswerverifiedShow Answer

Several organisms, primarily protists, have what are called intermediate mitotic organization. What is the most probable hypothesis about these intermediate forms of cell division?

Correct AnswerverifiedShow Answer

A cleavage furrow is ________.

Correct AnswerverifiedShow Answer

For a chemotherapeutic drug to be useful for treating cancer cells, which of the following characteristics is most desirable?

Correct AnswerverifiedShow Answer

FtsZ is a bacterial cytoskeletal protein that forms a contractile ring involved in binary fission. Its function is analogous to ________.

Correct AnswerverifiedShow Answer

Which of the following molecules is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?

Correct AnswerverifiedShow Answer

The decline of MPF activity at the end of mitosis is due to

Correct AnswerverifiedShow Answer

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