Question 1

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?

Accepted Answer

A)   G₁
B)   S
C)   G₂
D)   G₀E) A) and B)
F) A) and C)

Question 2

Nucleotides can be radiolabeled before they are incorporated into newly synthesized DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into a culture of dividing human cells at specific times. Which of the following questions might be answered by using the method described?

Accepted Answer

A)   How many cells are produced by the culture per hour?
B)   What is the length of the S phase of the cell cycle?
C)   How many picograms of DNA are made per cell cycle?
D)   When do spindle fibers attach to chromosomes?E) A) and B)
F) B) and D) B

Question 3

If a cell at metaphase of mitosis contains 20 sister chromatids, how many chromosomes will be present in a G₁ cell?

Accepted Answer

A)   5
B)   10
C)   20
D)   40E) A) and B)
F) C) and D)

Question 4

Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides to study the incorporation of labeled nucleotides into a culture of lymphocytes. They found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. What might they conclude from this observation?

Accepted Answer

A)   The pathogen consumed radiolabeled nucleotides.
B)   Infection causes lymphocytes to divide more rapidly.
C)   Infection causes lymphocytes to increase in size.
D)   Infection causes lymphocyte cultures to skip some parts of the cell cycle.E) C) and D)
F) B) and D) B

Question 5

Use the figure to answer the question below.

In the figure, MPF reaches its highest concentration during this stage.

Accepted Answer

A)   I
B)   II
C)   III
D)   IVE) None of the above
F) B) and C)

Question 6

Which of the following properties is associated with a cyclin-dependent kinase (Cdk) ?

Accepted Answer

A)   A Cdk is inactive, or "turned off," in the presence of a cyclin.
B)   The number of Cdk molecules increases during the S and G₂ phases and decrease during M.
C)   A Cdk is an enzyme that catalyzes the attachment of kinetochores to microtubules.
D)   A Cdk is an enzyme that attaches phosphate groups to other proteins.E) A) and B)
F) All of the above

Question 7

In a diploid cell with 5 chromosome pairs (2n = 10) , how many sister chromatids will be found in a nucleus at prophase of mitosis?

Accepted Answer

A)   5
B)   10
C)   20
D)   40E) A) and D)
F) B) and D)

Question 8

One difference between cancer cells and normal cells is that cancer cells

Accepted Answer

A)   are unable to synthesize DNA.
B)   are arrested at the S phase of the cell cycle.
C)   continue to divide even when they are tightly packed together.
D)   cannot function properly because they are affected by density-dependent inhibition.E) A) and B)
F) C) and D)

Question 9

The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle. If this does not happen, cells would most likely be arrested in ________.

Accepted Answer

A)   telophase
B)   prophase
C)   G₂
D)   metaphaseE) None of the above
F) All of the above

Question 10

The mitotic spindle plays a critical role in which of the following processes?

Accepted Answer

A)   splitting of the cell (cytokinesis)  following mitosis
B)   triggering the compaction and condensation of chromosomes
C)   dissolving the nuclear membrane
D)   separation of sister chromatidsE) A) and C)
F) B) and C)

Question 11

At which phase of the cell cycle do centrioles begin to move apart in animal cells?

Accepted Answer

A)   anaphase
B)   telophase
C)   metaphase
D)   prophaseE) A) and B)
F) A) and C) D

Question 12

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Accepted Answer

A)   spindle formation
B)   spindle attachment to kinetochores
C)   cell elongation during anaphase
D)   cleavage furrow formation and cytokinesisE) C) and D)
F) All of the above

Question 13

Use the figure to answer the question below.

In the figure, which number represents DNA synthesis?

Accepted Answer

A)   I
B)   II
C)   III
D)   IVE) B) and C)
F) B) and D)

Question 14

What is the name of the microtubule-organizing center found in animal cells as an identifiable structure present during all phases of the cell cycle?

Accepted Answer

A)   centriole
B)   centrosome
C)   centromere
D)   kinetochoreE) A) and B)
F) A) and C)

Question 15

Which of the following does not occur during mitosis?

Accepted Answer

A)   condensation of the chromosomes
B)   replication of the DNA
C)   separation of sister chromatids
D)   spindle formationE) B) and D)
F) None of the above

Question 16

Use the figure to answer the question below.

In the figure, at which of the numbered regions would you expect to find cells at metaphase?

Accepted Answer

A)   II and IV
B)   II only
C)   III only
D)   IV onlyE) A) and B)
F) A) and C)

Question 17

Starting with a fertilized egg (zygote) , a series of six cell divisions would produce an early embryo with how many cells?

Accepted Answer

A)   12
B)   16
C)   32
D)   64E) C) and D)
F) B) and D)

Question 18

Exposure of zebrafish nuclei to cytosol isolated from eggs at metaphase of mitosis resulted in phosphorylation of NEP55 and L68 proteins by cyclin-dependent kinase 2. NEP55 is a protein of the inner nuclear membrane, and L68 is a protein of the nuclear lamina. What is the most likely role of phosphorylation of these proteins in the process of mitosis?

Accepted Answer

A)   They enable the attachment of the spindle microtubules to kinetochore regions of the centromere.
B)   They are involved in chromosome condensation.
C)   They are involved in the disassembly of the nuclear envelope.
D)   They assist in the migration of centrosomes to opposite sides of the nucleus.E) A) and B)
F) A) and D)

Question 19

Density-dependent inhibition is explained by which of the following processes?

Accepted Answer

A)   As cells become more numerous, they begin to squeeze against each other, restricting their size.
B)   As cells become more numerous, the cell surface proteins of one cell contact the adjoining cells, and they signal each other to stop dividing.
C)   As cells become more numerous, the protein kinases they produce begin to compete with each other, such that the proteins produced by one cell essentially cancel those produced by its neighbor.
D)   As cells become more numerous, the level of waste products increases, which slows metabolism and inhibits growth.E) C) and D)
F) B) and C)

Question 20

Metaphase is characterized by ________.

Accepted Answer

A)   alignment of chromosomes on the equator of the cell
B)   separation of the centromeres
C)   cytokinesis
D)   separation of sister chromatidsE) A) and B)
F) A) and C)

Exam 12: The Cell Cycle

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?

Correct Answer
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Correct Answer
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B

If a cell at metaphase of mitosis contains 20 sister chromatids, how many chromosomes will be present in a G₁ cell?

Correct Answer
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Correct Answer
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B

Use the figure to answer the question below. In the figure, MPF reaches its highest concentration during this stage.

Correct Answer
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Which of the following properties is associated with a cyclin-dependent kinase (Cdk) ?

Correct Answer
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In a diploid cell with 5 chromosome pairs (2n = 10) , how many sister chromatids will be found in a nucleus at prophase of mitosis?

Correct Answer
verified

One difference between cancer cells and normal cells is that cancer cells

Correct Answer
verified

The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle. If this does not happen, cells would most likely be arrested in ________.

Correct Answer
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The mitotic spindle plays a critical role in which of the following processes?

Correct Answer
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At which phase of the cell cycle do centrioles begin to move apart in animal cells?

Correct Answer
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D

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Correct Answer
verified

Use the figure to answer the question below. In the figure, which number represents DNA synthesis?

Correct Answer
verified

What is the name of the microtubule-organizing center found in animal cells as an identifiable structure present during all phases of the cell cycle?

Correct Answer
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Which of the following does not occur during mitosis?

Correct Answer
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Use the figure to answer the question below. In the figure, at which of the numbered regions would you expect to find cells at metaphase?

Correct Answer
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Starting with a fertilized egg (zygote) , a series of six cell divisions would produce an early embryo with how many cells?

Correct Answer
verified

Correct Answer
verified

Density-dependent inhibition is explained by which of the following processes?

Correct Answer
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Metaphase is characterized by ________.

Correct Answer
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Exam 12: The Cell Cycle

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedB

If a cell at metaphase of mitosis contains 20 sister chromatids, how many chromosomes will be present in a G₁ cell?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedB

Use the figure to answer the question below. In the figure, MPF reaches its highest concentration during this stage.

Correct AnswerverifiedShow Answer

Which of the following properties is associated with a cyclin-dependent kinase (Cdk) ?

Correct AnswerverifiedShow Answer

In a diploid cell with 5 chromosome pairs (2n = 10) , how many sister chromatids will be found in a nucleus at prophase of mitosis?

Correct AnswerverifiedShow Answer

One difference between cancer cells and normal cells is that cancer cells

Correct AnswerverifiedShow Answer

The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle. If this does not happen, cells would most likely be arrested in ________.

Correct AnswerverifiedShow Answer

The mitotic spindle plays a critical role in which of the following processes?

Correct AnswerverifiedShow Answer

At which phase of the cell cycle do centrioles begin to move apart in animal cells?

Correct AnswerverifiedD

The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Correct AnswerverifiedShow Answer

Use the figure to answer the question below. In the figure, which number represents DNA synthesis?

Correct AnswerverifiedShow Answer

What is the name of the microtubule-organizing center found in animal cells as an identifiable structure present during all phases of the cell cycle?

Correct AnswerverifiedShow Answer

Which of the following does not occur during mitosis?

Correct AnswerverifiedShow Answer

Use the figure to answer the question below. In the figure, at which of the numbered regions would you expect to find cells at metaphase?

Correct AnswerverifiedShow Answer

Starting with a fertilized egg (zygote) , a series of six cell divisions would produce an early embryo with how many cells?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Density-dependent inhibition is explained by which of the following processes?

Correct AnswerverifiedShow Answer

Metaphase is characterized by ________.

Correct AnswerverifiedShow Answer

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B

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B

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D

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